Education Proves More Effective Than Reminders At Improving Hypertension Patient Medication Adherence

London, ON, Canada – Sub-optimal medication adherence with hypertension medication is associated with uncontrolled blood pressure and an increasing economic burden. Researchers, clinicians, and policy makers continue to explore new ways of promoting antihypertensive medication adherence, however, there is little consensus on the best way to do this.

The ISPOR Medication Adherence & Persistence Special Interest Group conducted a comprehensive systematic review of all evidence published on adherence-enhancing interventions in hypertension. The aim was to help stakeholders determine which strategies promote optimal adherence. The results of the review indicate that interventions aimed at increasing patients’ knowledge of medications carry the greatest potential in improving adherence to antihypertensive medication.

Education-based strategies prove to be more effective than a variety of other methods including reminders, packaging, and support groups.

Dr. Femida Gwadry-Sridhar, lead author on the study, says, “With increasing emphasis on affordable health care and comparative effectiveness, it is important that we address the challenge of non-adherence and recognize that it poses a significant threat to productivity in society. Novel and engaging ways of promoting sustained adherence behaviour that embrace technologies like the internet and mobile devices present exciting opportunities in health research. Our review provides an evidence-based approach to the future design and implementation of such studies.”

The full study, “Impact of Interventions on Medication Adherence and Blood Pressure Control in Patients with Essential Hypertension: A Systematic Review by the ISPOR Medication Adherence and Persistence Special Interest Group,” is published in Value in Health.


Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research as well as policy papers to help health care leaders make evidence-based decisions. The journal is published bi-monthly and has over 8,000 subscribers (clinicians, decision makers, and researchers worldwide).

International Society for Pharmacoeconomics and Outcomes Research (ISPOR) is a nonprofit, international, educational and scientific organization that strives to increase the efficiency, effectiveness, and fairness of health care resource use to improve health.

For more information: www.ispor.org

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